Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic <i>BRAF</i> V600–Mutant Anaplastic Thyroid Cancer

Vivek Subbiah, Robert J. Kreitman, Zev A. Wainberg, +10

Journal of Clinical Oncology

Trametinib TreatmentConclusion DabrafenibMedicineRadionuclide TherapyLocally Advanced +13

Combined BRAF, EGFR, and MEK Inhibition in Patients with <i>BRAF</i> V600E-Mutant Colorectal Cancer

Ryan B. Corcoran, Thierry André, Chloé E. Atreya, +21

Cancer Discovery

Large-Scale Molecular Comparison of Human Schwann Cells to Malignant Peripheral Nerve Sheath Tumor Cell Lines and Tissues

Shyra J. Miller, Fatima Rangwala, Jon Williams, +17

Cancer Research

Increased production of sonic hedgehog by ballooned hepatocytes

Fatima Rangwala, Cynthia D. Guy, Jiuyi Lü, +5

The Journal of Pathology

PathologyFatty Liver DiseaseCholangiopathiesCellular PhysiologySonic Hedgehog +19

Pediatric Plexiform Neurofibromas: Impact on Morbidity and Mortality in Neurofibromatosis Type 1

Carlos E. Prada, Fatima Rangwala, Lisa J. Martin, +4

The Journal of Pediatrics

Neuro-oncologyPediatric NeurosurgerySurgical PathologyPediatricsPathology +5

Hedgehog Signaling Antagonist Promotes Regression of Both Liver Fibrosis and Hepatocellular Carcinoma in a Murine Model of Primary Liver Cancer

George Philips, Isaac S. Chan, Marzena Swiderska, +15

PLoS ONE

Neuronal α-Bungarotoxin Receptors Differ Structurally from Other Nicotinic Acetylcholine Receptors

Fatima Rangwala, Renaldo C. Drisdel, Sergey Rakhilin, +5

Journal of Neuroscience

Updated efficacy of the MEK inhibitor trametinib (T), BRAF inhibitor dabrafenib (D), and anti-EGFR antibody panitumumab (P) in patients (pts) with <i>BRAF</i> V600E mutated (BRAFm) metastatic colorectal cancer (mCRC).

Chloé E. Atreya, Eric Van Cutsem, Johanna C. Bendell, +15

Journal of Clinical Oncology

ImmunologyBrafm MelanomaPathologyDermatologyBraf V600e Mutations +18

<i>BRAF</i> -Mutant Transcriptional Subtypes Predict Outcome of Combined BRAF, MEK, and EGFR Blockade with Dabrafenib, Trametinib, and Panitumumab in Patients with Colorectal Cancer

Gary Middleton, Yiqun Yang, Catarina D. Campbell, +19

Clinical Cancer Research

Treatment with Combination of Dabrafenib and Trametinib in Patients with Recurrent/Refractory BRAF V600E-Mutated Hairy Cell Leukemia (HCL)

Robert J. Kreitman, Philippe Moreau, Martin Hutchings, +14

Blood