The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer

Valentina Grossi, Giovanna Forte, Paola Sanese, +10

Nucleic Acids Research

Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

Valentina Celestini, Tuğsan Tezil, Luciana Russo, +17

Cell Death and Disease

Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality

Paola Sanese, Candida Fasano, Giacomo Buscemi, +21

iScience

Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids

Martina Lepore Signorile, Valentina Grossi, Simone Di Franco, +15

Cell Death and Disease

Peptide matching between Epstein-Barr virus and human proteins

Giovanni Capone, Michele Calabrò, Guglielmo Lucchese, +4

Pathogens and Disease

Epstein-barr Virus ProteinsSystems BiologyHuman PeptideAutoimmune DiseaseMolecular Virology +11

Codon number shapes peptide redundancy in the universal proteome composition

Anthony Kusalik, Brett Trost, Mik Bickis, +3

Peptides

Universal Proteome CompositionProtein FoldingNatural SciencesMedicinePeptide Library +6

Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3

Marco Parenti, Marina Naldi, Elisabetta Manoni, +18

European Journal of Medicinal Chemistry

Combinatorial ChemistryMedicinal ChemistryBiochemistrySite-specific Covalent InhibitionNatural Sciences +8

Gastric polyposis and desmoid tumours as a new familial adenomatous polyposis clinical variant associated with <i>APC</i> mutation at the extreme 3′-end

Vittoria Disciglio, Candida Fasano, Filomena Cariola, +9

Journal of Medical Genetics

EBV-Associated Cancer and Autoimmunity: Searching for Therapies

Giovanni Capone, Candida Fasano, Guglielmo Lucchese, +2

Vaccines

Cancer-associated VirusAutoimmune DiseaseAllergyEpstein-barr VirusImmunology +11

c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer

Martina Lepore Signorile, Valentina Grossi, Candida Fasano, +9

Cancers

Cancer ResearchCell RegulationMedicineReceptor Tyrosine KinasePathology +13