Telomere length, telomerase activity and osteogenic differentiation are maintained in adipose-derived stromal cells from senile osteoporotic SAMP6 mice

Ali Mirsaidi, Karin N. Kleinhans, Markus Rimann, +4

Journal of Tissue Engineering and Regenerative Medicine

Therapeutic potential of adipose-derived stromal cells in age-related osteoporosis

Ali Mirsaidi, Konstantin Genelin, Jolanda R. Vetsch, +10

Biomaterials

Bone DiseaseAdipose-derived Stromal CellsOsteoarthritisMedicineCell Biology +2

Detrimental Role for Human High Temperature Requirement Serine Protease A1 (HTRA1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

André N. Tiaden, Marina Klawitter, Vanda Lux, +8

Journal of Biological Chemistry

Degenerative SpineIntervertebral DiscAmyotrophic Lateral SclerosisMedicineProteasome +8

Human Serine Protease HTRA1 Positively Regulates Osteogenesis of Human Bone Marrow-derived Mesenchymal Stem Cells and Mineralization of Differentiating Bone-forming Cells Through the Modulation of Extracellular Matrix Protein

André N. Tiaden, Maike Breiden, Ali Mirsaidi, +6

Stem Cells

SclerostinImmunologySerine ProteasesMatrix MineralizationExtracellular Matrix Protein +15

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

Mareike Lehmann, Eija Pirinen, Ali Mirsaidi, +4

Nucleic Acids Research

Molecular BiologyInsulin SignalingMetabolic SyndromeTranscriptional RegulationPparγ-dependent Gene Expression +21

<i>ARTD1</i> deletion causes increased hepatic lipid accumulation in mice fed a high‐fat diet and impairs adipocyte function and differentiation

Süheda Erener, Ali Mirsaidi, Mareike Hesse, +6

The FASEB Journal

Use of biomimetic microtissue spheroids and specific growth factor supplementation to improve tenocyte differentiation and adaptation to a collagen-based scaffold in vitro

Felix Theiss, Ali Mirsaidi, Rami Mhanna, +5

Biomaterials

Tissue EngineeringRegenerative MedicineBiocompatible MaterialEngineeringBiomaterials +12

ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β

Agnieszka Robaszkiewicz, Chao Qu, Ewelina Wiśnik, +7

Scientific Reports

Magnetic fields modulate metabolism and gut microbiome in correlation with <i>Pgc‐1α</i> expression: Follow‐up to an in vitro magnetic mitohormetic study

Yee Kit Tai, Charmaine Ng, Kristy Purnamawati, +28

The FASEB Journal

DysbiosisHost-microbe InteractionsKinesiologyExerciseGut Microbiology +19

Prostaglandin E2 inhibits matrix mineralization by human bone marrow stromal cell-derived osteoblasts via Epac-dependent cAMP signaling

Ali Mirsaidi, André N. Tiaden, Peter J. Richards

Scientific Reports