Seung‐Hwa Kwak

Synthesis and structure-activity relationships of quinolinone and quinoline-based P2X7 receptor antagonists and their anti-sphere formation activities in glioblastoma cells

Seung‐Hwa Kwak, S. H. Shin, Ji-Hyun Lee et al. · European Journal of Medicinal Chemistry · 2018 · 31 citations · Full text

Neuro-oncology, Glioma, Medicine +9

Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7–NMDA Receptor Antagonists

Olga Karoutzou, Seung‐Hwa Kwak, So‐Deok Lee et al. · Molecules · 2018 · 27 citations · Full text

Drug Target, Alzheimer's Disease, Glutamatergic Nmda Receptors +15

Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors

Seung‐Hwa Kwak, C. Skyler Cochrane, Amanda F. Ennis et al. · Bioorganic Chemistry · 2020 · 25 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +4

Structure–Activity Relationship of Sulfonyl Piperazine LpxH Inhibitors Analyzed by an LpxE-Coupled Malachite Green Assay

Minhee Lee, Jinshi Zhao, Seung‐Hwa Kwak et al. · ACS Infectious Diseases · 2019 · 24 citations · Full text

Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles

Marta Barniol‐Xicota, Seung‐Hwa Kwak, So‐Deok Lee et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 14 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Diversity Oriented Synthesis +10