A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans

Naja Zenius Jespersen, Therese Juhlin Larsen, Lone Peijs, +10

Cell Metabolism

ObesityMetabolic SyndromeDevelopmental BiologyBody CompositionHealth Sciences +10

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation

Denis P. Blondin, Søren Nielsen, Eline N. Kuipers, +16

Cell Metabolism

ObesityMetabolic SyndromeEnergy HomeostasisInsulin SignalingMolecular Physiology +9

Osteogenesis depends on commissioning of a network of stem cell transcription factors that act as repressors of adipogenesis

Alexander Rauch, Anders Haakonsson, Jesper Grud Skat Madsen, +14

Nature Genetics

Developmental BiologyBone Morphogenic ProteinMedicineBone RemodelingMorphogenesis +6

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

Susanna Søberg, Camilla H. Sandholt, Naja Zenius Jespersen, +15

Cell Metabolism

ObesityMetabolic SyndromeNutritionSweet IntakeAppetite Control +8

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis

Joan Sánchez-Gurmaches, Yuefeng Tang, Naja Zenius Jespersen, +10

Cell Metabolism

Systems BiologyEnergy MetabolismSignal TransductionBiochemistryBioenergetics +11

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Elahu G. Sustarsic, Tao Ma, Matthew D. Lynes, +41

Cell Metabolism

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

Atul S. Deshmukh, Lone Peijs, Jacqueline L. Beaudry, +20

Cell Metabolism

Proteomic TechnologyProtein SecretionSignal TransductionMedicineNatural Sciences +10

Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

Jasper M. A. de Jong, Wenfei Sun, Nuno D. Pires, +17

Nature Metabolism

ObesityMetabolic SyndromeEnergy HomeostasisDevelopmental BiologyBody Composition +11

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

Olivia Sveidahl Johansen, Tao Ma, Jakob Bondo Hansen, +48

Cell

Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

Naja Zenius Jespersen, Amir Feizi, Eline Sandvig Andersen, +13

Molecular Metabolism