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The Lancet

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The Lancet

VaccinationVaccine SafetyPhase 1/2Vaccine DevelopmentPreliminary Report +5

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Merryn Voysey, Sue Ann Costa Clemens, Shabir A. Madhi, +758

The Lancet

Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial

William W. Busse, Eugene R. Bleecker, J Mark FitzGerald, +439

The Lancet Respiratory Medicine

AsthmaRheumatologyExtension TrialAllergyAllergy Medicine +8

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)

Amy Flaxman, Natalie G. Marchevsky, Daniel Jenkin, +184

The Lancet

Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

Pedro M. Folegatti, Mustapha Bittaye, Amy Flaxman, +27

The Lancet Infectious Diseases

A Critical Role for MAPK Signalling Pathways in the Transcriptional Regulation of Toll Like Receptors

Marylène Péroval, Amy Boyd, John R. Young, +1

PLoS ONE

Tlr BiologyTlr ActivationInnate Immune SystemImmunologyImmune Regulation +19

TLR15 Is Unique to Avian and Reptilian Lineages and Recognizes a Yeast-Derived Agonist

Amy Boyd, Marylène Péroval, John A. Hammond, +3

The Journal of Immunology

Microbial PathogensGeneticsInnate Immune SystemImmune RegulationImmunology +26

Badger macrophages fail to produce nitric oxide, a key anti-mycobacterial effector molecule

Kirstin Bilham, Amy Boyd, Stephen G. Preston, +4

Scientific Reports

Improved adjuvanting of seasonal influenza vaccines: Preclinical studies of <scp>MVA‐NP+M</scp>1 coadministration with inactivated influenza vaccine

Caitlin E. Mullarkey, Amy Boyd, Arjan van Laarhoven, +9

European Journal of Immunology

ImmunologyCd4 T Cell ResponsesMva-np+m1 Influenza VaccinesFlu VaccinationImmunotherapy +14