Kazuya Otake

Multidrug resistance transporters Snq2p and Pdr5p mediate caffeine efflux in <i>Saccharomyces cerevisiae</i>

Yoshiyuki Tsujimoto, Yoshihiro Shimizu, Kazuya Otake et al. · Bioscience Biotechnology and Biochemistry · 2015 · 29 citations · Full text

Molecular Pharmacology, Multicopy Vector Yep24, Drug Resistance Analysis +15

Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: Peroxisome proliferator-activated receptor γ selective agonists with protein-tyrosine phosphatase 1B inhibition

Kazuya Otake, Satoru Azukizawa, Masaki Fukui et al. · Bioorganic & Medicinal Chemistry · 2011 · 29 citations · Full text

Biochemistry, Medicine, Natural Sciences +9

A Novel Series of (S)-2,7-Substituted-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor .ALPHA./.GAMMA. Dual Agonists with Protein-Tyrosine Phosphatase 1B Inhibitory Activity

Kazuya Otake, Satoru Azukizawa, Masaki Fukui et al. · Chemical and Pharmaceutical Bulletin · 2011 · 17 citations · Full text

Dual Agonists, Pharmacotherapy, Protein-tyrosine Phosphatase 1B +17

2-Acyl-tetrahydroisoquinoline-3-carboxylic Acids: Lead Compounds with Triple Actions, Peroxisome Proliferator-Activated Receptor .ALPHA./.GAMMA. Agonist and Protein-Tyrosine Phosphatase 1B Inhibitory Activities

Kazuya Otake, Satoru Azukizawa, Kenji Takahashi et al. · Chemical and Pharmaceutical Bulletin · 2011 · 15 citations · Full text

Pharmacotherapy, Protein-tyrosine Phosphatase 1B, Chemical Biology +17

Novel 2,7-Substituted (&lt;i&gt;S&lt;/i&gt;)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acids: Peroxisome Proliferator-Activated Receptor γ Partial Agonists with Protein–Tyrosine Phosphatase 1B Inhibition

Kazuya Otake, Satoru Azukizawa, Shigemitsu Takeda et al. · Chemical and Pharmaceutical Bulletin · 2015 · 14 citations · Full text

Protein–tyrosine Phosphatase 1B, Partial Pparγ Agonism, Pharmacotherapy +17