The soft palate is an important site of adaptation for transmissible influenza viruses

Seema S. Lakdawala, Akila Jayaraman, Rebecca Halpin, +15

Nature

Virus StructureImportant SiteViral EvolutionPathogenesisTransmissible Influenza Viruses +6

Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin

Kannan Tharakaraman, Akila Jayaraman, Rahul Raman, +6

Cell

VaccinationVirus StructureViral PathogenesisImmunologyVirology +4

Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets

Melissa B. Pearce, Akila Jayaraman, Claudia Pappas, +10

Proceedings of the National Academy of Sciences

N-Linked Glycosylation of the Hemagglutinin Protein Influences Virulence and Antigenicity of the 1918 Pandemic and Seasonal H1N1 Influenza A Viruses

Xiangjie Sun, Akila Jayaraman, Pavithra Maniprasad, +7

Journal of Virology

VaccinationHa Glycosylation SitesVirus StructureViral EvolutionGlycosylation Patterns +11

Structural Determinants for Naturally Evolving H5N1 Hemagglutinin to Switch Its Receptor Specificity

Kannan Tharakaraman, Rahul Raman, Karthik Viswanathan, +5

Cell

Signal TransductionBiochemistryG Protein-coupled ReceptorStructural DeterminantsReceptor Specificity +4

Effect of D222G Mutation in the Hemagglutinin Protein on Receptor Binding, Pathogenesis and Transmissibility of the 2009 Pandemic H1N1 Influenza Virus

Jessica A. Belser, Akila Jayaraman, Rahul Raman, +6

PLoS ONE

Hemagglutinin ProteinViral EvolutionEmerging Infectious DiseasesVirus PathogenesisPathogenesis +13

Decoding the Distribution of Glycan Receptors for Human-Adapted Influenza A Viruses in Ferret Respiratory Tract

Akila Jayaraman, Aarthi Chandrasekaran, Karthik Viswanathan, +3

PLoS ONE

VaccinationVirus StructureFerret Respiratory TractMedicineViral Pathogenesis +9

A Single Base-Pair Change in 2009 H1N1 Hemagglutinin Increases Human Receptor Affinity and Leads to Efficient Airborne Viral Transmission in Ferrets

Akila Jayaraman, Claudia Pappas, Rahul Raman, +5

PLoS ONE

Single Base-pair ChangeViral EvolutionViral PathogenesisImmunologyImmunodominance +10

Quantitative Description of Glycan-Receptor Binding of Influenza A Virus H7 Hemagglutinin

Karunya Srinivasan, Rahul Raman, Akila Jayaraman, +2

PLoS ONE

Microbial PathogensViral PathogenesisImmunologyImmunodominanceBinding Affinity +16

Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice

Taronna R. Maines, Akila Jayaraman, Jessica A. Belser, +12

Science