Crosstalk between SUMO and Ubiquitin on PCNA Is Mediated by Recruitment of the Helicase Srs2p

Efterpi Papouli, Shuhua Chen, Adelina A. Davies, +4

Molecular Cell

Pcna IsProtein FunctionBiochemistryProtein FoldingNatural Sciences +5

Mutations in TJP2 cause progressive cholestatic liver disease

Melissa Sambrotta, Sandra Strautnieks, Efterpi Papouli, +19

Nature Genetics

HepatologyBiliary TractLiver PhysiologyPathologyHepatology Inflammation +3

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

Karen A. Hunt, Vanisha Mistry, Nicholas Bockett, +33

Nature

Genome-wide Association StudyAllelic VariantAutoimmune DiseaseGenotype-phenotype AssociationGenetics +8

Dependence of the Cytotoxicity of DNA-Damaging Agents on the Mismatch Repair Status of Human Cells

Efterpi Papouli, Petr Ćejka, Josef Jiricny

Cancer Research

Dna DamageDna AnalysisMolecular BiologyCell DeathPathology +17

Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes

Natalie J. Prescott, Benjamin Lehne, Kristina L. Stone, +26

PLoS Genetics

Genetic predisposition to ductal carcinoma in situ of the breast

Christos Petridis, Mark N. Brook, Vandna Shah, +91

Breast Cancer Research

Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast

Elinor J. Sawyer, Rebecca Roylance, Christos Petridis, +58

PLoS Genetics

Breast OncologyCancer PathologyInvasive Lobular CarcinomaGeneticsGenetic Epidemiology +20

Deficiency in BRCA2 leads to increase in non-conservative homologous recombination

Florence Larminat, Maryse Germanier, Efterpi Papouli, +1

Oncogene

Genome InstabilityGeneticsMolecular BiologyGenetic MechanismMolecular Genetics +5

Overexpression of Metallothionein-II Sensitizes Rodent Cells to Apoptosis Induced by DNA Cross-linking Agent through Inhibition of NF-κB Activation

Efterpi Papouli, Martine Defais, Florence Larminat

Journal of Biological Chemistry

Stratified gene expression analysis identifies major amyotrophic lateral sclerosis genes

Ashley Jones, Claire Troakes, Andrew King, +13

Neurobiology of Aging

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisFunctional GenomicsMedicineGenetics +6