Folic Acid Derived Hydrogel Enhances the Survival and Promotes Therapeutic Efficacy of iPS Cells for Acute Myocardial Infarction

Hekai Li, Jie Gao, Yuna Shang, +5

ACS Applied Materials & Interfaces

Tissue EngineeringEngineeringBiomaterials DesignCardiac RegenerationBiomedical Engineering +22

Extracellular vesicles engineering by silicates-activated endothelial progenitor cells for myocardial infarction treatment in male mice

Bin Yu, Hekai Li, Zhaowenbin Zhang, +9

Nature Communications

Injectable AuNP-HA matrix with localized stiffness enhances the formation of gap junction in engrafted human induced pluripotent stem cell-derived cardiomyocytes and promotes cardiac repair

Hekai Li, Bin Yu, Pingzhen Yang, +7

Biomaterials

Regenerative MedicineMechanobiologyTissue EngineeringCardiac MuscleEngineering +12

An injectable and conductive TEMPOL/polypyrrole integrated peptide co-assembly hydrogel promotes functional maturation of cardiomyocytes for myocardial infarction repair

Jie Zhan, Xu Liao, Xianglin Fan, +4

Composites Part B Engineering

Tissue EngineeringHydrogelsRegenerative MedicineBiopolymer GelCardiac Reprogramming +13

Ion Therapy: A Novel Strategy for Acute Myocardial Infarction

Min Yi, Hekai Li, Xiaoya Wang, +11

Advanced Science

<i>In situ</i> activated mesenchymal stem cells (MSCs) by bioactive hydrogels for myocardial infarction treatment

Long Gao, Min Yi, Min Xing, +6

Journal of Materials Chemistry B

Treatment of Myocardial Infarction with Gene-modified Mesenchymal Stem Cells in a Small Molecular Hydrogel

Zhiye Wu, Guoqin Chen, Jianwu Zhang, +7

Scientific Reports

Tissue EngineeringCardiac MuscleEngineeringAdult Stem CellCardiac Regeneration +18

Lentiviral vector-mediated co-overexpression of VEGF and Bcl-2 improves mesenchymal stem cell survival and enhances paracrine effects in vitro

Xiaobin Ni, Caiwen Ou, Jingbin Guo, +5

International Journal of Molecular Medicine

Cell TherapyLentiviral Vector-mediated Co-overexpressionImmunologyCardiac RegenerationRegenerative Medicine +17

Targeted heart repair by Tβ4-loaded cardiac-resident macrophage-derived extracellular vesicles modified with monocyte membranes

Peier Chen, Yuxuan Pan, Xiaodong Ning, +10

Acta Biomaterialia

Cell-based Drug DeliveryExtracellular VesiclesMonocyte MembranesHeart RepairImmunology +8

Fabrication of Tβ4-Exosome-releasing artificial stem cells for myocardial infarction therapy by improving coronary collateralization

Peier Chen, Xiaodong Ning, Weirun Li, +9

Bioactive Materials

Cell TherapyNanotherapeuticsEngineeringAdult Stem CellImmunology +21