Brittany de Temple

Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial

Stephen A. Harrison, Peter Ruane, B. Freilich et al. · Nature Medicine · 2021 · 342 citations

Medicine, Internal Medicine, Pharmacotherapy +10

Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial

Stephen A. Harrison, Juan P. Frías, Guy Neff et al. · ˜The œLancet. Gastroenterology & hepatology · 2023 · 235 citations

Medicine, Pharmacology, Pharmacotherapy +8

A randomized, double-blind, placebo-controlled phase IIa trial of efruxifermin for patients with compensated NASH cirrhosis

Stephen A. Harrison, Peter Ruane, B. Freilich et al. · JHEP Reports · 2022 · 101 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Efruxifermin in Compensated Liver Cirrhosis Caused by MASH

Mazen Noureddin, Mary E. Rinella, Naga Chalasani et al. · New England Journal of Medicine · 2025 · 91 citations

Medicine, Internal Medicine, Pharmacotherapy +17

Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study

Stephen A. Harrison, Juan P. Frías, Kathryn Jean Lucas et al. · Clinical Gastroenterology and Hepatology · 2024 · 85 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17