Steven Gendreau

Randomized Phase II Study Evaluating Akt Blockade with Ipatasertib, in Combination with Abiraterone, in Patients with Metastatic Prostate Cancer with and without PTEN Loss

Johann S. de Bono, Ugo De Giorgi, Daniel Nava Rodrigues et al. · Clinical Cancer Research · 2018 · 310 citations

Medicine, Oncology, Pharmacology +15

Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant

Jill M. Spoerke, Steven Gendreau, Kimberly Walter et al. · Nature Communications · 2016 · 297 citations · Full text

Medicine, Genetics, Oncology +17

Pictilisib for oestrogen receptor-positive, aromatase inhibitor-resistant, advanced or metastatic breast cancer (FERGI): a randomised, double-blind, placebo-controlled, phase 2 trial

Ian E. Krop, Ingrid A. Mayer, Vinod Ganju et al. · The Lancet Oncology · 2016 · 295 citations

Medicine, Oncology, Pharmacology +12

Analytical Validation of a Hybrid Capture–Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA

Travis Clark, Jon Chung, Mark Kennedy et al. · Journal of Molecular Diagnostics · 2018 · 201 citations · Full text

Medicine, Molecular Genetics, Oncology +17

EXEL-7647 Inhibits Mutant Forms of ErbB2 Associated with Lapatinib Resistance and Neoplastic Transformation

Torsten Trowe, Sotiria Boukouvala, Keith Calkins et al. · Clinical Cancer Research · 2008 · 133 citations

Medicine, Molecular Biology, Oncology +14