Jay C. Groppe

Structural basis of BMP signalling inhibition by the cystine knot protein Noggin

Jay C. Groppe, Jason Greenwald, Ezra Wiater et al. · Nature · 2002 · 543 citations

Life Sciences, Biochemistry, Molecular Biology +10

Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1

Frederick S. Kaplan, Meiqi Xu, Petra Seemann et al. · Human Mutation · 2008 · 448 citations

Medicine, Genetics, Molecular Genetics +15

Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding

Jay C. Groppe, Cynthia S. Hinck, Payman Samavarchi‐Tehrani et al. · Molecular Cell · 2008 · 286 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly

Jason Greenwald, Jay C. Groppe, Peter C. Gray et al. · Molecular Cell · 2003 · 263 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice

Xiaofang Wang, Shuzhen Wang, Changcheng Li et al. · PLoS Genetics · 2012 · 203 citations · Full text

Medicine, Genetics, Molecular Genetics +17