Mei-Lin Okino

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino et al. · Nature · 2021 · 453 citations · Full text

Genome-wide Association Study, Metabolic Syndrome, Type 1 +10

Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk

Joshua Chiou, Chun Zeng, Cheng Zhang et al. · Nature Genetics · 2021 · 180 citations · Full text

Chromatin, Chromatin Structure, Natural Sciences +10

Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

William W. Greenwald, Joshua Chiou, Jian Yan et al. · Nature Communications · 2019 · 112 citations · Full text

An Integrated Map of Cell Type–Specific Gene Expression in Pancreatic Islets

Ruth M. Elgamal, Parul Kudtarkar, Rebecca Melton et al. · Diabetes · 2023 · 69 citations · Full text

Engineering, Integrated Map, Genetics +25

Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes

Gaowei Wang, Joshua Chiou, Chun Zeng et al. · Nature Genetics · 2023 · 67 citations · Full text

Metabolic Syndrome, Genetic Determinant, Medicine +11