Mucosal immunoglobulins at respiratory surfaces mark an ancient association that predates the emergence of tetrapods

Zhen Xu, Fumio Takizawa, David Parra, +4

Nature Communications

The expression of CD8α discriminates distinct T cell subsets in teleost fish

Fumio Takizawa, Johannes M. Dijkstra, Paul Kotterba, +6

Developmental & Comparative Immunology

BiologyTeleost FishAdaptive Immune SystemT Cell ImmunityFish Immunology +3

Conservation of characteristics and functions of CD4 positive lymphocytes in a teleost fish

Hideaki Toda, Yasutaka Saito, Takuhito Koike, +9

Developmental & Comparative Immunology

BiologyTeleost FishAdaptive Immune SystemAquacultureImmunology +6

Specialization of mucosal immunoglobulins in pathogen control and microbiota homeostasis occurred early in vertebrate evolution

Zhen Xu, Fumio Takizawa, Elisa Casadei, +6

Science Immunology

Constitutive high expression of interleukin-4/13A and GATA-3 in gill and skin of salmonid fishes suggests that these tissues form Th2-skewed immune environments

Fumio Takizawa, Erling Olaf Koppang, Maki Ohtani, +4

Molecular Immunology

InflammationConstitutive High ExpressionCytokineAllergyPathogenesis +9

Alloantigen-specific killing is mediated by CD8-positive T cells in fish

Hideaki Toda, Yasuhiro Shibasaki, Takuhito Koike, +5

Developmental & Comparative Immunology

Autoimmune DiseaseAlloantigen-specific KillingT-regulatory CellImmunologyCell Death +5

Novel Teleost CD4-Bearing Cell Populations Provide Insights into the Evolutionary Origins and Primordial Roles of CD4+ Lymphocytes and CD4+ Macrophages

Fumio Takizawa, Susana Magadán, David Parra, +4

The Journal of Immunology

Characterization and localization of side population (SP) cells in zebrafish kidney hematopoietic tissue

Isao Kobayashi, Kazuyuki Saito, Tadaaki Moritomo, +3

Blood

Prevailing Role of Mucosal Igs and B Cells in Teleost Skin Immune Responses to Bacterial Infection

Xiaoting Zhang, Yongyao Yu, Haoyue Xu, +13

The Journal of Immunology

Cold-blooded vertebrates evolved organized germinal center–like structures

Yasuhiro Shibasaki, Sergey Afanasyev, Álvaro Fernández-Montero, +9

Science Immunology