Vancomycin: structure and transformation to CDP-I

Constance M. Harris, Hana Kopecka, Thomas M. Harris

Journal of the American Chemical Society

DatabasesMedia StandardsMolecular BiologyAltmetric Attention ScoreBibliometrics +14

The role of the chlorine substituents in the antibiotic vancomycin: preparation and characterization of mono- and didechlorovancomycin

Constance M. Harris, Kannan Rajamoorthi, Hana Kopecka, +1

Journal of the American Chemical Society

Altmetric Attention ScoreOrganic ChemistryAntimicrobial ChemotherapyAntibiotic ResistanceAntibiotic Vancomycin +17

A Short, Efficient Synthesis of the Novel Cholinergic Channel Activator, ABT 418, from L-Proline

Richard L. Elliott, Hana Kopecka, Nan‐Horng Lin, +2

Synthesis

Medicinal ChemistryBiochemistryMedicineNatural SciencesAbt 418 +10

Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721

David J. Madar, Hana Kopecka, Daisy Pireh, +5

Tetrahedron Letters

Cross-coupling ReactionEngineeringOrganic ChemistryCatalysisChemistry +5

Evidence that type A CCK receptors facilitate dopamine efflux in rat brain

Thomas W. Vickroy, Bruce R. Bianchi, James F. Kerwin, +2

European Journal of Pharmacology

Cck ReceptorsNeurophysiologyMedicineFunctional SelectivityNeurotransmitter +9

Development of CCK-tetrapeptide analogs as potent and selective CCK-A receptor agonists

Kazumi Shiosaki, C W Lin, Hana Kopecka, +6

Journal of Medicinal Chemistry

ImmunologyAltmetric Attention ScorePharmacotherapySystem PharmacologyPre-clinical Pharmacology +21

Discovery of 2-[4-{{2-(2<i>S</i>,5<i>R</i>)-2-Cyano-5-ethynyl-1-pyrrolidinyl]-2-oxoethyl]amino]- 4-methyl-1-piperidinyl]-4-pyridinecarboxylic Acid (ABT-279):  A Very Potent, Selective, Effective, and Well-Tolerated Inhibitor of Dipeptidyl Peptidase-IV, Useful for the Treatment of Diabetes

David J. Madar, Hana Kopecka, Daisy Pireh, +28

Journal of Medicinal Chemistry

Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit

Bradley J. Backes, Kenton L. Longenecker, Gregory L. Hamilton, +17

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryDrug DesignMedicine +9

Characterization of two novel cholecystokinin tetrapeptide (30-33) analogues, A-71623 and A-70874, that exhibit high potency and selectivity for cholecystokinin-A receptors.

C W Lin, Kazumi Shiosaki, Ted R. Miller, +7

Molecular Pharmacology

Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonists

James F. Kerwin, Alex M. Nadzan, Hana Kopecka, +4

Journal of Medicinal Chemistry

Cck AntagonistsNew ImplicationsImmunologyAltmetric Attention ScorePharmacotherapy +19