Douglas J. Kornbrust

Relative susceptibility of microsomes from lung, heart, liver, kidney, brain and testes to lipid peroxidation: Correlation with vitamin E content

Douglas J. Kornbrust, Richard D. Mavis · Lipids · 1980 · 409 citations

Lung Lipid Extract, Vitamin E Content, Rat Liver Lipid +13

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA

Jeremy D. Heidel, Zhongping Yu, Joanna Yi-Ching Liu et al. · Proceedings of the National Academy of Sciences · 2007 · 381 citations · Full text

Nanoparticles, Engineering, Immunology +21

First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder

Sancy A. Leachman, Robyn P. Hickerson, Mary Schwartz et al. · Molecular Therapy · 2009 · 261 citations · Full text

Activation of the Alternative Pathway of Complement by a Phosphorothioate Oligonucleotide: Potential Mechanism of Action

Scott P. Henry, Patricia C. Giclas, Michael K. Pangburn et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 203 citations

Complement activation is responsible for acute toxicities in rhesus monkeys treated with a phosphorothioate oligodeoxynucleotide

Scott P. Henry, Greg Beattie, Grace Chao Yeh et al. · International Immunopharmacology · 2002 · 143 citations

Complement System, Phosphorothioate Oligodeoxynucleotide, Rhesus Monkeys +8