A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer

Stephano S. Mello, Liz J. Valente, Nitin Raj, +17

Cancer Cell

Pancreatic CancerMedicinePathologyCancer BiologyTumor Suppressor +5

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

Shadmehr Demehri, Zhenyi Liu, Jonghyeob Lee, +6

PLoS Biology

Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells

Jonghyeob Lee, Takuya Sugiyama, Yinghua Liu, +9

eLife

Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation

Takuya Sugiyama, Cecil M. Benitez, Amar Ghodasara, +8

Proceedings of the National Academy of Sciences

Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation

Jing Cai, Jonghyeob Lee, Raphael Kopan, +1

Developmental Biology

Notch1 ExpressionDevelopmental BiologyDevelopmental GeneticsGeneticsHair Shaft Differentiation +6

Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes

Jonghyeob Lee, Jacob M. Basak, Shadmehr Demehri, +1

Development

Paracrine Tgfbeta SignalingTgfbeta LigandsDermatologyCellular PhysiologyTumor Biology +16

Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Jonghyeob Lee, Emily R. Snyder, Yinghua Liu, +9

Nature Communications

Genetic Mosaic Analysis Indicates That the Bulb Region of Coat Hair Follicles Contains a Resident Population of Several Active Multipotent Epithelial Lineage Progenitors

Raphael Kopan, Jonghyeob Lee, Meei‐Hua Lin, +7

Developmental Biology

BiologyCell LineageDevelopmental BiologyBulb RegionMedicine +6

Dicer Regulates Differentiation and Viability during Mouse Pancreatic Cancer Initiation

John P. Morris, Renee L. Greer, Holger A. Russ, +8

PLoS ONE

PathologyCancer BiologyTumor BiologyDicer Regulates DifferentiationPancreatic Cancer +14

Efficient generation of pancreatic β-like cells from the mouse gallbladder

Yuhan Wang, Feorillo Galivo, Carl Pelz, +4

Stem Cell Research

Regenerative MedicineGallbladder CellsInsulin SignalingDevelopmental BiologyBiliary Tract +11