Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.

Jérôme Pugin, C.-C. Schürer-Maly, Didier Leturcq, +3

Proceedings of the National Academy of Sciences

Proteinlipid InteractionImmunologyImmunologic MechanismLipid TailInflammation +15

Characterization of Protease-activated Receptor-2 Immunoreactivity in Normal Human Tissues

Michael R. D’Andrea, Claudia K. Derian, Didier Leturcq, +7

Journal of Histochemistry & Cytochemistry

ImmunologyPathologyPar-2c AntibodyCellular PhysiologyGastrointestinal Peptide Hormone +14

Antigen Presentation and T Cell Development in H2-M-Deficient Mice

Wai‐Ping Fung‐Leung, Charles D. Surh, Monika Liljedahl, +5

Science

HistocompatibilityLymphocyte DevelopmentHla ImmunogeneticsImmunologyAntigen Processing +14

Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs.

Thomas R. Martin, John C. Mathison, Peter S. Tobias, +4

Journal of Clinical Investigation

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyPulmonary Alveolar Proteinosis +20

The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenicity

F. Schödel, A Moriarty, D L Peterson, +6

Journal of Virology

VaccinationInserted EpitopeViral HepatitisVaccine TargetPathogenesis +12

Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin.

J D Lee, Vladimir V. Kravchenko, Theo N. Kirkland, +6

Proceedings of the National Academy of Sciences

Integral Membrane FormsImmunologyImmune RegulationImmunologic MechanismInnate Immunity +16

Relationship between soluble CD14, lipopolysaccharide binding protein, and the alveolar inflammatory response in patients with acute respiratory distress syndrome.

Thomas R. Martin, Gordon D. Rubenfeld, J. Ruzinski, +7

American Journal of Respiratory and Critical Care Medicine

Acute Lung InjuryAsthmaInflammatory Lung DiseaseLung InflammationRespiratory Distress Syndrome (Pulmonary Critical Care) +15

Immunization of hu-PBL–SCID mice and the rescue of human monoclonal Fab fragments through combinatorial libraries

Michel A. Duchosal, Sabine A. Eming, Peter Fischer, +7

Nature

Knockout MouseHu-pbl–scid MiceCombinatorial LibrariesImmunologyImmunophenotyping +4

Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: Implications for cellular iron homeostasis

Luisa Salter–Cid, Anders Brunmark, Yuanhao Li, +4

Proceedings of the National Academy of Sciences

Hereditary HemochromatosisIron MetabolismMolecular BiologyCellular Iron HomeostasisIron Deficiency +20

Antibodies against CD14 protect primates from endotoxin-induced shock.

Didier Leturcq, A Moriarty, G. Douglas Talbott, +3

Journal of Clinical Investigation

Acute Lung InjuryInflammationCytokineEndotoxin-induced ShockAllergy +12