Eric A. Hanse

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells

Henrique Borges da Silva, Lalit K. Beura, Haiguang Wang et al. · Nature · 2018 · 251 citations · Full text

Immunological Memory, Molecular Physiology, Signal Transduction +10

α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer

Thai Q. Tran, Eric A. Hanse, Amber N. Habowski et al. · Nature Cancer · 2020 · 163 citations · Full text

Cancer Research, Oncology, Medicine +8

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

Benjamin A. Olenchock, Javid J. Moslehi, Alan H. Baik et al. · Cell · 2016 · 142 citations · Full text

α-Ketoglutarate Suffice, Egln1 Inhibition, Medicine +5

MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1

Ying Yang, Mari B. Ishak Gabra, Eric A. Hanse et al. · Nature Communications · 2019 · 132 citations · Full text

Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancer

Eric A. Hanse, Chunhai Ruan, Maureen Kachman et al. · Oncogene · 2017 · 116 citations · Full text

Tumor Biology, Cellular Enzymology, Biochemistry +11