Sylvia De Brakeleer

Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib

Amir Noeparast, Erik Teugels, Philippe Giron et al. · Oncotarget · 2016 · 100 citations · Full text

Braf Kinase Activity, Impaired Braf Kinases, Pathology +17

De novo Alu element insertions targeted to a sequence common to the BRCA1 and BRCA2 genes

Erik Teugels, Sylvia De Brakeleer, Guido Goelen et al. · Human Mutation · 2005 · 99 citations · Full text

Cancer predisposing missense and protein truncating<i>BARD1</i>mutations in non-<i>BRCA1</i>or<i>BRCA2</i>breast cancer families

Sylvia De Brakeleer, Jacques De Grève, Remy Loris et al. · Human Mutation · 2010 · 86 citations · Full text

Engineering, Cancer Pathology, Genetics +18

Correlation of EGFR, IDH1 and PTEN status with the outcome of patients with recurrent glioblastoma treated in a phase II clinical trial with the EGFR-blocking monoclonal antibody cetuximab

Shasha Lv, Erik Teugels, Jan Sadones et al. · International Journal of Oncology · 2012 · 64 citations · Full text

Gene Amplification, Pathology, High-grade Gliomas +17

Identification of candidate cancer predisposing variants by performing whole-exome sequencing on index patients from BRCA1 and BRCA2-negative breast cancer families

Rajendra Bahadur Shahi, Sylvia De Brakeleer, Ben Caljon et al. · BMC Cancer · 2019 · 49 citations · Full text