Eoin F. J. Cosgrave

EndoS2 is a unique and conserved enzyme of serotype M49 group A <i>Streptococcus</i> that hydrolyses N-linked glycans on IgG and α1-acid glycoprotein

Jonathan Sjögren, Weston B. Struwe, Eoin F. J. Cosgrave et al. · Biochemical Journal · 2013 · 106 citations · Full text

Glycoproteomics, Protein Glycosylation, Biochemistry +14

EndoS and EndoS2 hydrolyze Fc-glycans on therapeutic antibodies with different glycoform selectivity and can be used for rapid quantification of high-mannose glycans

Jonathan Sjögren, Eoin F. J. Cosgrave, Maria Allhorn et al. · Glycobiology · 2015 · 74 citations · Full text

Glycobiology, Immunology, Carbohydrate-protein Interaction +20

Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab

Jerrard M. Hayes, Åsa Frostell, Robert Karlsson et al. · Molecular & Cellular Proteomics · 2017 · 73 citations · Full text

Fc Gamma Receptor Glycosylation Modulates the Binding of IgG Glycoforms: A Requirement for Stable Antibody Interactions

Jerrard M. Hayes, Åsa Frostell, Eoin F. J. Cosgrave et al. · Journal of Proteome Research · 2014 · 68 citations

Immunocytochemical Technique, Glycobiology, Immunology +23

Galactosyltransferase 4 is a major control point for glycan branching in <i>N</i>-linked glycosylation

Andrew G. McDonald, Jerrard M. Hayes, Tania Bezak et al. · Journal of Cell Science · 2014 · 40 citations · Full text