Structural basis for SARM1 inhibition and activation under energetic stress

Michael Sporny, Julia Guez-Haddad, Tami Khazma, +8

eLife

Ubiquitin-independent proteasomal degradation driven by C-degron pathways

Yaara Makaros, Anat Raiff, Richard T. Timms, +9

Molecular Cell

Structural Evidence for an Octameric Ring Arrangement of SARM1

Michael Sporny, Julia Guez-Haddad, Mario Lebendiker, +5

Journal of Molecular Biology

Crystal StructureStructural EvidenceMolecular BiologyStructure ElucidationCrystallography +1

Structural Principles in Robo Activation and Auto-inhibition

Reut Barak, Galit Yom-Tov, Julia Guez-Haddad, +8

Cell

Signal TransductionBiochemistryMacromolecular MachineMechanism Of ActionCytoskeleton +3

Structural History of Human SRGAP2 Proteins

Michael Sporny, Julia Guez-Haddad, Annett Kreusch, +7

Molecular Biology and Evolution

Molecular BiologyCell CultureCellular NeurobiologySynaptic SignalingSocial Sciences +22

Leukocyte Cytoskeleton Polarization Is Initiated by Plasma Membrane Curvature from Cell Attachment

Chunguang Ren, Qianying Yuan, Martha Braun, +15

Developmental Cell

MechanobiologyMedicineCell AdhesionPlasma Membrane CurvatureCell Trafficking +10

Robo Ig4 Is a Dimerization Domain

Galit Yom-Tov, Reut Barak, Omri Matalon, +3

Journal of Molecular Biology

Crystal StructureMolecular BiologyRobo Ig4CrystallographyStructural Biology +1

The Neuronal Migration Factor srGAP2 Achieves Specificity in Ligand Binding through a Two-Component Molecular Mechanism

Julia Guez-Haddad, Michael Sporny, Yehezkel Sasson, +5

Structure

Molecular NeuroscienceSignal TransductionNeurophysiologyG Protein-coupled ReceptorReceptor (Biochemistry) +12

A duplex structure of SARM1 octamers stabilized by a new inhibitor

Tami Khazma, Yarden Golan-Vaishenker, Julia Guez-Haddad, +8

Cellular and Molecular Life Sciences

Molecular symmetry-constrained systematic search approach to structure solution of the coiled-coil SRGAP2 F-BARx domain

Michael Sporny, Julia Guez-Haddad, David G. Waterman, +2

Acta Crystallographica Section D Structural Biology

Srgap2 GeneratesMolecular BiologyCytoskeletonProtein FoldingSecretory Pathway +17