Prion-like acceleration of a synucleinopathy in a transgenic mouse model

Anne‐Laure Mougenot, Simon Nicot, Anna Bencsik, +5

Neurobiology of Aging

Knockout MouseCreutzfeldt-jakob DiseaseTransgenic Mouse ModelsPrion DiseaseNeuroscience +4

Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease

Daisy Bougard, Jean‐Philippe Brandel, Maxime Bélondrade, +14

Science Translational Medicine

The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation

Bruno Mugat, Simon Nicot, Carolina Varela‐Chavez, +7

Nature Communications

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Nadine Mestre‐Francés, Simon Nicot, Sylvie Rouland, +5

Emerging infectious diseases

Creutzfeldt-jakob DiseaseOral TransmissionPathologyIntracerebral InoculationEducation +16

Transmission of Prion Strains in a Transgenic Mouse Model Overexpressing Human A53T Mutated α-Synuclein

Anne‐Laure Mougenot, Anna Bencsik, Simon Nicot, +7

Journal of Neuropathology & Experimental Neurology

Knockout MouseNeurodegenerative DiseasesNeurobiology Of DiseaseTransgenic Mouse ModelsMedicine +13

Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation

Aurélie Alleaume‐Butaux, Simon Nicot, Mathéa Pietri, +10

PLoS Pathogens

Creutzfeldt-jakob DiseaseMolecular BiologyCellular NeurobiologySynaptic SignalingSynapse Dysfunction +18

Rapid and Highly Sensitive Detection of Variant Creutzfeldt - Jakob Disease Abnormal Prion Protein on Steel Surfaces by Protein Misfolding Cyclic Amplification: Application to Prion Decontamination Studies

Maxime Bélondrade, Simon Nicot, Vincent Béringue, +3

PLoS ONE

Strain-Specific Barriers against Bovine Prions in Hamsters

Simon Nicot, Thierry Baron

Journal of Virology

BiologyAnimal StudyBovine PrionsRodent-borne DiseasesAnimal Science +10

Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies

Maxime Bélondrade, Christelle Jas-Duval, Simon Nicot, +9

mSphere

A family of carboxypeptidases catalyzing α- and β-tubulin tail processing and deglutamylation

Simon Nicot, Ghislain Gillard, Hathaichanok Impheng, +5

Science Advances

β-Tubulin Tail ProcessingProtein FunctionProtein ExpressionBiochemistryMicrotubule Functions +11