Alexander R. Shikhman

Author

Scripps Research Institute ORCID

Also Known As

A R Shikhman, A.R. Shikhman, Alexander R Shikhman, Alexander R. Shikhman, Alexander Shikhman

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

Scripps Research Institute Scripps Clinic University of Oklahoma Health Sciences Center Case Western Reserve University

About

Alexander R. Shikhman is an author at Scripps Research Institute specializing in medicine, osteoarthritis, and inflammation.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	584
2	Cell Biology	3	3	286
3	Biochemistry	2	2	130
4	Natural Sciences	1	1	75
5	Allergy	1	1	98

Alexander R. Shikhman

Publications

1.4K

Citations

H-Index

Page 1

	Year	Citations
<i>N</i> -Acetylglucosamine Prevents IL-1β-Mediated Activation of Human Chondrocytes Alexander R. Shikhman, Klaus Kühn, Nada Alaaeddine, The Journal of Immunology	2001	193
Cytokine Regulation of Facilitated Glucose Transport in Human Articular Chondrocytes Alexander R. Shikhman, Diana C. Brinson, J Valbracht, The Journal of Immunology ImmunologyCellular PhysiologyInflammationBone Morphogenic ProteinOsteoarthritis	2001	158
Role of heavy chain constant domains in antibody-antigen interaction. Apparent specificity differences among streptococcal IgG antibodies expressing identical variable domains Laurence J.N. Cooper, Alexander R. Shikhman, D D Glass, The Journal of Immunology	1993	100
A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes <i>N</i> -acetyl- <i>beta</i> - <scp>d</scp> -glucosamine. Alexander R. Shikhman, Neil S. Greenspan, Madeleine W. Cunningham The Journal of Immunology	1993	98
Immunological mimicry between N-acetyl-beta-D-glucosamine and cytokeratin peptides. Evidence for a microbially driven anti-keratin antibody response. Alexander R. Shikhman, Madeleine W. Cunningham The Journal of Immunology Clinical ImmunologyHumoral ResponseImmunologyImmune RegulationGlycobiology	1994	98
Cytokeratin peptide SFGSGFGGGY mimics <i>N</i> -acetyl- <i>beta</i> -D-glucosamine in reaction with antibodies and lectins, and induces in vivo anti-carbohydrate antibody response. Alexander R. Shikhman, Neil S. Greenspan, Madeleine W. Cunningham The Journal of Immunology	1994	95
Chondroprotective activity of N-acetylglucosamine in rabbits with experimental osteoarthritis Alexander R. Shikhman Annals of the Rheumatic Diseases	2004	90
Synthesis and High-Throughput Screening of <i>N</i>-Acetyl-β-hexosaminidase Inhibitor Libraries Targeting Osteoarthritis Junjie Liu, Mehdi M. D. Numa, Haitian Liu, The Journal of Organic Chemistry GlycobiologyC1 Nitrogen IminocyclitolsPharmaceutical ChemistryMedicinal ChemistryDiversity Oriented Synthesis	2004	75
Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis Junjie Liu, Alexander R. Shikhman, Martin Lotz, Chemistry & Biology Rheumatoid DisorderHexosaminidase InhibitorsNew Drug CandidatesPharmacologyChronic Musculoskeletal Condition	2001	70
Role of nitric oxide, reactive oxygen species, and p38 MAP kinase in the regulation of human chondrocyte apoptosis Klaus Kühn, Alexander R. Shikhman, Martin Lotz Journal of Cellular Physiology P38 Map KinaseChemoprevention StrategyImmunotoxicologyNitric OxideLipid Peroxidation	2003	70

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