mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence

Soo Seok Hwang, Jaechul Lim, Zhibin Yu, +8

Science

HHQ and PQS, two <i>Pseudomonas aeruginosa</i> quorum‐sensing molecules, down‐regulate the innate immune responses through the nuclear factor‐κB pathway

Kiwan Kim, Young Uk Kim, Byung Hee Koh, +5

Immunology

Inflammatory Lung DiseaseMicrobial PathogensInnate Immune SystemImmunologyInnate Immunity +20

Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma

Byung Hee Koh, Soo Seok Hwang, Joo‐Young Kim, +6

Proceedings of the National Academy of Sciences

AsthmaEnvironmental AllergyInflammatory Lung DiseaseLung InflammationImmunology +16

Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation

Soo Seok Hwang, Young Uk Kim, Sumin Lee, +8

Proceedings of the National Academy of Sciences

Inflammatory Lung DiseaseTh2 Cell DifferentiationMolecular RegulationImmunologyTranscription Factor Yy1 +17

YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity

Soo Seok Hwang, Sung Woong Jang, Min Kyung Kim, +7

Nature Communications

PTEN drives Th17 cell differentiation by preventing IL-2 production

Hyeong Su Kim, Sung Woong Jang, Wonyong Lee, +4

The Journal of Experimental Medicine

The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery

Wonyong Lee, Hyeong Su Kim, Soo Seok Hwang, +1

Experimental & Molecular Medicine

Emerging role of anti-proliferative protein BTG1 and BTG2

Sang Hyeon Kim, In Ryeong Jung, Soo Seok Hwang

BMB Reports

B-cell LeukemiaHematological MalignancyMixed-phenotype Acute LeukemiaCentral Biological StepsApoptosis +11

Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy

Hong‐Yeoul Ryu, Nicole R. Wilson, Sameet Mehta, +2

Genes & Development

CytogeneticsGeneticsSumo Protease Ulp2ProteasomeGenomic Mechanism +14

Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression

Adam Williams, Gap Ryol Lee, Charalampos G. Spilianakis, +3

Proceedings of the National Academy of Sciences