Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics

Jau‐Yi Li, Benoît Chassaing, Abdul Malik Tyagi, +9

Journal of Clinical Investigation

T Lymphocytes Amplify the Anabolic Activity of Parathyroid Hormone through Wnt10b Signaling

Masakazu Terauchi, Jau‐Yi Li, Brahmchetna Bedi, +13

Cell Metabolism

Signal TransductionPhysiologyImmunologyWnt10b SignalingParathyroid Hormone +9

Ovariectomy disregulates osteoblast and osteoclast formation through the T-cell receptor CD40 ligand

Jau‐Yi Li, Hesham A. Tawfeek, Brahmchetna Bedi, +6

Proceedings of the National Academy of Sciences

Osteoclastogenic CytokinesSclerostinSc ProductionT-regulatory CellImmune Regulation +22

Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota

Jau‐Yi Li, Mingcan Yu, Subhashis Pal, +6

Journal of Clinical Investigation

SclerostinHost-microbe InteractionsImmunologyParathyroid GlandT Cells +21

Novel Regulators of Kidney Development from the Tips of the Ureteric Bud

Kai M. Schmidt‐Ott, Jun Yang, Xia Chen, +9

Journal of the American Society of Nephrology

Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells

Mingcan Yu, Subhashis Pal, Cameron W. Paterson, +6

Journal of Clinical Investigation

PTH induces bone loss via microbial-dependent expansion of intestinal TNF+ T cells and Th17 cells

Mingcan Yu, Abdul Malik Tyagi, Jau‐Yi Li, +5

Nature Communications

IL-17A Is Increased in Humans with Primary Hyperparathyroidism and Mediates PTH-Induced Bone Loss in Mice

Jau‐Yi Li, Patrizia D’Amelio, Jerid W. Robinson, +11

Cell Metabolism

InflammationBone DiseaseAutoimmune DiseaseParathyroid HormoneImmunology +8

Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

Brahmchetna Bedi, Jau‐Yi Li, Hesham A. Tawfeek, +7

Proceedings of the National Academy of Sciences

SclerostinImmunologyParathyroid DiseaseParathyroid GlandT Cells +18

Disruption of PTH Receptor 1 in T Cells Protects against PTH-Induced Bone Loss

Hesham A. Tawfeek, Brahmchetna Bedi, Jau‐Yi Li, +5

PLoS ONE