Thomas J. Giacobbe

Reactions of Alpha Methylene Lactone Tumor Inhibitors with Model Biological Nucleophiles

S. Morris Kupchan, Dyral C. Fessler, M. Allan Eakin et al. · Science · 1970 · 297 citations

Model Biological Nucleophiles, Bioorganic Chemistry, Reactive Nucleophilic Reagents +17

Formation of .alpha.-acetoxy ketones by oxidation of enamines with thallium triacetates

Martin E. Kuehne, Thomas J. Giacobbe · The Journal of Organic Chemistry · 1968 · 62 citations

.Alpha.-acetoxy Ketones, Bioorganic Chemistry, Aldehyde Dehydrogenase +14

Tumor inhibitors. LVII. Reaction of endocyclic .alpha.,.beta.-unsaturated .gamma.-lactones with thiols

S. Morris Kupchan, Thomas J. Giacobbe, Ira S. Krull et al. · The Journal of Organic Chemistry · 1970 · 61 citations

Altmetric Attention Score, Pharmacotherapy, Pharmaceutical Chemistry +16

Reversible thiol addition as a protecting reaction for conjugated α-methylene groups of lactones

S. Morris Kupchan, Thomas J. Giacobbe, Ira S. Krull · Tetrahedron Letters · 1970 · 24 citations

Engineering, Biochemistry, Natural Sciences +8

The ultraviolet spectra of the chloropyridines and chlorinated pyridines possessing a sulfur (‐SR), nitrogen (‐NR₂), or oxygen (‐OR) substituent in either the 2 or 4‐position: A convenient method for distinguishing such positional isomers

Thomas J. Giacobbe, Stanley D. McGregor, Floyd L. Beman · Journal of Heterocyclic Chemistry · 1974 · 10 citations

Engineering, Organic Chemistry, Ultraviolet Spectra +18