Dennis J. Wu

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal

Mattias N. D. Svensson, Martina Zoccheddu, Shen K. Yang et al. · Science Advances · 2020 · 66 citations · Full text

A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune Diseases

Yantao He, Sijiu Liu, Ambili Menon et al. · Journal of Medicinal Chemistry · 2013 · 65 citations · Full text

Drug Target, Immunology, Lymphoid-specific Tyrosine Phosphatase +26

Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity

Mattias N. D. Svensson, Karen M. Doody, Benjamin Joachim Schmiedel et al. · Journal of Clinical Investigation · 2019 · 64 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +25

PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes

Angel Bottini, Dennis J. Wu, Rizi Ai et al. · Annals of the Rheumatic Diseases · 2019 · 58 citations · Full text

High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45

Stephanie M. Stanford, Rekha G. Panchal, Logan M. Walker et al. · Proceedings of the National Academy of Sciences · 2012 · 32 citations · Full text