Brain tumour cells interconnect to a functional and resistant network

Matthias Osswald, Erik Jung, Felix Sahm, +36

Nature

Neuro-oncologyBrain CircuitryGliomaBrain Tumour CellsCell Interaction +6

Glutamatergic synaptic input to glioma cells drives brain tumour progression

Varun Venkataramani, Dimitar Ivanov Tanev, Christopher Strahle, +25

Nature

Neuro-oncologySynaptic PlasticityBrain Tumour ProgressionTumor InnervationGlioma +11

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

Lukas Bunse, Stefan Pusch, Theresa Bunse, +51

Nature Medicine

Cancer ImmunosurveillanceMedicineT-regulatory CellImmunologyTumor Immunity +7

Tumor microtubes convey resistance to surgical lesions and chemotherapy in gliomas

Sophie Weil, Matthias Osswald, Gergely Solecki, +7

Neuro-Oncology

Autonomous rhythmic activity in glioma networks drives brain tumour growth

David Hausmann, Dirk C. Hoffmann, Varun Venkataramani, +29

Nature

Brain CircuitryNeurodynamicsGliomaNeurophysiologyComputational Neuroscience +9

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

Philipp Sievers, Thomas Hielscher, Daniel Schrimpf, +21

Acta Neuropathologica

Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas

Mirco Friedrich, Roman Sankowski, Lukas Bunse, +34

Nature Cancer

Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma

Erik Jung, Matthias Osswald, Miriam Ratliff, +10

Nature Communications

MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

Michael Kilian, Ron Sheinin, Chin Leng Tan, +18

Cancer Cell

Hematological MalignancyCancer ImmunosurveillanceCytotoxic T CellsMedicineMalignant Blood Disorder +9

Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study

Areeba Patel, Helin Dogan, Alexander Payne, +24

Acta Neuropathologica

NanoporesNeuro-oncologyNanomedicineSystems BiologyEngineering +13