David E. Timm

Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor

Patrick C. May, Robert A. Dean, Stephen L. Lowe et al. · Journal of Neuroscience · 2011 · 365 citations · Full text

Robust Central Reduction, Amyloid-β Peptide, Neurochemical Biomarkers +21

Asymmetries in the nucleosome core particle at 2.5 Å resolution

Joel M. Harp, B. Leif Hanson, David E. Timm et al. · Acta Crystallographica Section D Biological Crystallography · 2000 · 217 citations

The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans

Patrick C. May, Brian A. Willis, Stephen L. Lowe et al. · Journal of Neuroscience · 2015 · 195 citations · Full text

Amyloid β, Neurodegenerative Diseases, Amyloid Lowering +15

Crystal structure of human homogentisate dioxygenase.

David E. Timm, Greg P. Titus, H.A. Mueller et al. · Nature Structural Biology · 2000 · 153 citations

Structure-function Enzyme Kinetics, Crystal Structure, Structural Biology +1

Phosphides of the B31 (MnP) Structure Type.

Stig Rundqvist, Lars Gunnar Sillén, David E. Timm et al. · Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1962 · 145 citations · Full text

Inorganic Chemistry, Crystal Structure, Engineering +5