Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans

Daniel G. MacArthur, Jane T. Seto, Joanna M. Raftery, +12

Nature Genetics

Knockout MouseMuscle PhysiologyMuscle FunctionMolecular PhysiologySkeletal Muscle +10

An Actn3 knockout mouse provides mechanistic insights into the association between  -actinin-3 deficiency and human athletic performance

Daniel G. MacArthur, Jane T. Seto, Stephen Chan, +11

Human Molecular Genetics

Identification of FHL1 as a regulator of skeletal muscle mass: implications for human myopathy

Belinda S. Cowling, Meagan J. McGrath, Mai-Anh Nguyen, +9

The Journal of Cell Biology

Muscle FunctionCalcineurin InhibitionMolecular RegulationPathologySkeletal Muscle Mass +19

An Actin Filament Population Defined by the Tropomyosin Tpm3.1 Regulates Glucose Uptake

Anthony J. Kee, Lingyan Yang, Christine A. Lucas, +10

Traffic

Hypertrophy and dietary tyrosine ameliorate the phenotypes of a mouse model of severe nemaline myopathy

Mai-Anh Nguyen, Josephine E. Joya, Anthony J. Kee, +11

Brain

Muscle FunctionCytoskeletonMitochondrial MyopathyThin FilamentMuscle Physiology +25

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments

Galina Schevzov, Anthony J. Kee, Bin Wang, +15

Molecular Biology of the Cell

Tm5nm1-containing Actin FilamentsCell ProliferationCytoskeletonCancer BiologyCellular Physiology +18

Aged skeletal muscle retains the ability to fully regenerate functional architecture

Antonio S. J. Lee, Judy E. Anderson, Josephine E. Joya, +5

BioArchitecture

Muscle FunctionAgingBiogerontologyOrthopaedic SurgeryRegenerative Medicine +17

Sorting of a nonmuscle tropomyosin to a novel cytoskeletal compartment in skeletal muscle results in muscular dystrophy

Anthony J. Kee, Galina Schevzov, Visalini Nair‐Shalliker, +8

The Journal of Cell Biology

Tropomyosin Regulates Cell Migration during Skin Wound Healing

Justin G. Lees, Yu Wooi Ching, Damian Adams, +7

Journal of Investigative Dermatology

Cutaneous BiologySkin Wound HealingCell MigrationCytoskeletonWound Healing +7

Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

Nicole Vlahovich, Anthony J. Kee, Chris van der Poel, +7

Molecular Biology of the Cell

Muscle FunctionCytoskeletonMechanotransductionProtein TropomyosinNormal Excitation–contraction Coupling +17