M Suchan

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

Uğur Şahin, Evelyna Derhovanessian, Matthias Miller et al. · Nature · 2017 · 2.4K citations

Vaccination, Allergy, Medicine +11

An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors

Katharina Reinhard, Benjamin Rengstl, Petra Oehm et al. · Science · 2020 · 479 citations

Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens

David Weber, Jonas Ibn-Salem, Patrick Sorn et al. · Nature Biotechnology · 2022 · 51 citations · Full text

Accurate Detection, Cancer Immunosurveillance, Tumor Heterogeneity +10

Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

Jan D. Beck, Mustafa Diken, M Suchan et al. · Cancer Cell · 2024 · 51 citations

Immunological Memory, Autoimmune Disease, Adaptive Immune System +7

A TCR-like CAR Promotes Sensitive Antigen Recognition and Controlled T-cell Expansion Upon mRNA Vaccination

Matthias Birtel, Ralf-Holger Voss, Katharina Reinhard et al. · Cancer Research Communications · 2022 · 20 citations · Full text