Peter E. Soden

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Mark A. Dawson, Rab K. Prinjha, Antje Dittmann et al. · Nature · 2011 · 1.5K citations · Full text

Life Sciences, Hematology, Molecular Biology +10

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

Omer Gilan, Inmaculada Rioja, Kathy Knezevic et al. · Science · 2020 · 428 citations · Full text

Life Sciences, Immunology, Pharmacology +13

The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor

Romain Gosmini, Van Loc Nguyen, Jérôme Toum et al. · Journal of Medicinal Chemistry · 2014 · 187 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

MAPK-activated Protein Kinase 2 Deficiency in Microglia Inhibits Pro-inflammatory Mediator Release and Resultant Neurotoxicity

Ainsley A. Culbert, Stephen D. Skaper, David Howlett et al. · Journal of Biological Chemistry · 2006 · 170 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Dishevelled Regulates the Metabolism of Amyloid Precursor Protein via Protein Kinase C/Mitogen-Activated Protein Kinase and c-Jun Terminal Kinase

Amritpal Mudher, Susan C. Chapman, Jill Richardson et al. · Journal of Neuroscience · 2001 · 119 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17