Concepedia

Maohua Cai

MC

8

Publications

246

Citations

8

H-Index

2018

Active since

Affiliations

Zhejiang Chinese Medical University(Current)

Zhejiang Cancer Hospital

Chinese Academy of Sciences

Zhejiang University of Technology

University of Chinese Academy of Sciences

Maohua Cai is an author at Zhejiang Chinese Medical University specializing in drug discovery, medicinal chemistry, and drug development.

Top concepts

Publications per year

2018–2024

8

Publications

8

Depletion of HDAC1, 7 and 8 by Histone Deacetylase Inhibition Confers Elimination of Pancreatic Cancer Stem Cells in Combination with Gemcitabine

Maohua Cai, Xiaogang Xu, Shili Yan et al. · Scientific Reports · 2018 · 73 citations · Full text

Regorafenib suppresses colon tumorigenesis and the generation of drug resistant cancer stem-like cells via modulation of miR-34a associated signaling

Maohua Cai, Xiaogang Xu, Shili Yan et al. · Journal of Experimental & Clinical Cancer Research · 2018 · 40 citations · Full text

Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4

Maohua Cai, Furong Ma, Can Hu et al. · Bioorganic & Medicinal Chemistry · 2023 · 29 citations

, , +11

Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis

Jinyun Dong, Furong Ma, Maohua Cai et al. · Journal of Medicinal Chemistry · 2024 · 24 citations · Full text

ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation

Furong Ma, Yulong Li, Maohua Cai et al. · European Journal of Medicinal Chemistry · 2024 · 22 citations

, , +11

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