Abdalkarim Tanina

The small-molecule SMARt751 reverses <i>Mycobacterium tuberculosis</i> resistance to ethionamide in acute and chronic mouse models of tuberculosis

Marion Flipo, Rosangela Frita, Marilyne Bourotte et al. · Science Translational Medicine · 2022 · 27 citations · Full text

Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening

Léo Faïon, Kamel Djaout, Rosangela Frita et al. · European Journal of Medicinal Chemistry · 2020 · 22 citations · Full text

Pulmonary Tuberculosis, Drug Target, Engineering +11

A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR

Abdalkarim Tanina, Alexandre Wohlkönig, Sameh H. Soror et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2018 · 16 citations · Full text

Crystal Structure, Pulmonary Tuberculosis, Biochemistry +13

A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2

Hugues Prevet, Martin Moune, Abdalkarim Tanina et al. · European Journal of Medicinal Chemistry · 2019 · 15 citations · Full text

Combinatorial Chemistry, Pulmonary Tuberculosis, Natural Product Synthesis +11

Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2

Alexandre Wohlkönig, Han Remaut, Martin Moune et al. · Biochemical and Biophysical Research Communications · 2017 · 11 citations

Pulmonary Tuberculosis, Bacteriology, Molecular Biology +7