Graeme Laver

BCX-1812 (RWJ-270201):  Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design

Y.S. Babu, Pooran Chand, Shanta Bantia et al. · Journal of Medicinal Chemistry · 2000 · 376 citations · Full text

Crystal Structure, Medicinal Chemistry, Antimicrobial Drug Discovery +15

Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain

S.J. Crennell, Elspeth F. Garman, Graeme Laver et al. · Structure · 1994 · 202 citations · Full text

Crystal Structure, Catalytic Domain, Virulence Factor +6

Influenza Neuraminidase Inhibitors:  Structure-Based Design of a Novel Inhibitor Series

Vincent S. Stoll, Kent D. Stewart, Clarence J. Maring et al. · Biochemistry · 2003 · 128 citations

The Structures ofSalmonella typhimuriumLT2 Neuraminidase and its Complexes with Three Inhibitors at High Resolution

S.J. Crennell, Elspeth F. Garman, Cédric Philippon et al. · Journal of Molecular Biology · 1996 · 85 citations

High Resolution, Biomolecular Structure Prediction, Antiparasitic Agent +7

A Sialic Acid-derived Phosphonate Analog Inhibits Different Strains of Influenza Virus Neuraminidase with Different Efficiencies

Clinton L. White, Musiri N. Janakiraman, Graeme Laver et al. · Journal of Molecular Biology · 1995 · 73 citations

Different Efficiencies, Medicine, Virology +7