Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity

Zhouteng Tao, Hongfeng Wang, Xia Qin, +6

Human Molecular Genetics

Motor dysfunction and neurodegeneration in a C9orf72 mouse line expressing poly-PR

Zongbing Hao, Liu Liu, Zhouteng Tao, +8

Nature Communications

miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder

Lei Fan, Rongtao Lai, Ningning Ma, +10

Journal of Hepatology

Transcriptional RegulationHepatologyLiver PhysiologyPathologyMetabolic Regulation +8

Nuclear miR-30b-5p suppresses TFEB-mediated lysosomal biogenesis and autophagy

Huijie Guo, Mei Pu, Yusi Tai, +9

Cell Death and Differentiation

Cell AutophagyAutophagyMicrorna DetectionGene ExpressionMedicine +2

MiR-629-5p promotes the invasion of lung adenocarcinoma via increasing both tumor cell invasion and endothelial cell permeability

Yu Li, Huibiao Zhang, Lei Fan, +12

Oncogene

MedicineLung AdenocarcinomaCancer Cell BiologyMicrorna DetectionEndothelial Cell Permeability +7

C9orf72 associates with inactive Rag GTPases and regulates mTORC1‐mediated autophagosomal and lysosomal biogenesis

Mingmei Wang, Hongfeng Wang, Zhouteng Tao, +6

Aging Cell

MitophagyMolecular RegulationGeneticsMtorc1 ActivityImmunology +15

Protease Omi cleaving Hax-1 protein contributes to OGD/R-induced mitochondrial damage in neuroblastoma N2a cells and cerebral injury in MCAO mice

Jiayuan Wu, Mei Li, Lijuan Cao, +8

Acta Pharmacologica Sinica

Mitochondrial FunctionProtease OmiAutophagyCell DeathMcao Mice +9

Dependence of PINK1 accumulation on mitochondrial redox system

Feng Gao, Yan Zhang, Xiao‐Ou Hou, +3

Aging Cell

miR-34a-5p regulates PINK1-mediated mitophagy via multiple modes

Yusi Tai, Mei Pu, Luyang Yuan, +8

Life Sciences

MitophagyAutophagySmall RnaMicrorna DetectionMedicine +3

MiR-4465 directly targets PTEN to inhibit AKT/mTOR pathway–mediated autophagy

Zhouteng Tao, Chenxi Feng, Chenmei Mao, +7

Cell Stress and Chaperones

Cell AutophagySignal TransductionAutophagyMicrorna DetectionMedicine +2