George R. Mount

Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity

Wallace T. Ashton, Rosemary M. Sisco, G. R. KIECZYKOWSKI et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 53 citations · Full text

Functional Activity, Functional Selectivity, High Potency +8

A Potent, Nonpeptidyl 1<i>H</i>-Quinolone Antagonist for the Gonadotropin-Releasing Hormone Receptor

Robert J. DeVita, Thomas F. Walsh, Jonathan R. Young et al. · Journal of Medicinal Chemistry · 2001 · 47 citations · Full text

Identification of Phe313 of the Gonadotropin-Releasing Hormone (GnRH) Receptor as a Site Critical for the Binding of Nonpeptide GnRH Antagonists

Jisong Cui, Roy G. Smith, George R. Mount et al. · Molecular Endocrinology · 2000 · 46 citations

Site Critical, Pharmacotherapy, Experimental Pharmacology +21

2-Arylindoles as gonadotropin releasing hormone (GnRH) antagonists: optimization of the tryptamine side chain

Jonathan R. Young, Song X. Huang, Thomas F. Walsh et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 37 citations · Full text

Endocrine Mechanism, Medicine, Hormonal Receptor +11

Potent nonpeptide GnRH receptor antagonists derived from substituted indole-5-carboxamides and -acetamides bearing a pyridine side-chain terminus

Wallace T. Ashton, Rosemary M. Sisco, Yi Yang et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 36 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +11