Concepedia

Author

Lesley S. Sheehan

University of Cambridge

Also Known As

Lesley S. Sheehan

7

Publications

360

Citations

7

H-Index

35

Concepts

All Affiliations

University of CambridgeIsomerase Therapeutics (United Kingdom)
LS

About

Lesley S. Sheehan is an author at University of Cambridge specializing in synthetic biology, biotechnology, and biochemistry.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Engineering

5

5

221

2

Natural Sciences

5

5

221

3

Biochemistry

5

5

221

4

Biomolecular Engineering

3

3

85

5

Chemical Biology

2

2

70

Lesley S. Sheehan

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7

Publications

360

Citations

7

H-Index

YearCitations

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Aleksandra Wlodek, Steve Kendrew, Nigel J. Coates,

Nature Communications

2017

91

Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors

Ming‐Qiang Zhang, Sabine Gaisser, Mohammad Nur‐e‐Alam,

Journal of Medicinal Chemistry

2008

86

Engineering of the Spinosyn PKS:  Directing Starter Unit Incorporation

Lesley S. Sheehan, Rachel E. Lill, Barrie Wilkinson,

Journal of Natural Products

2006

50

Rapamycin biosynthesis: elucidation of gene product function

Matthew A. Gregory, Hui Hong, Rachel E. Lill,

Organic & Biomolecular Chemistry

2006

48

Conditional language models enable the efficient design of proficient enzymes

Geraldene Munsamy, R. Illanes, Silvia Fruncillo,

2024

36

Engineered biosynthesis of hybrid macrolide polyketides containing d-angolosamine and d-mycaminose moieties

Ursula Schell, Stephen Haydock, Andrew L. Kaja,

Organic & Biomolecular Chemistry

2008

29

Structure guided design of improved anti-proliferative rapalogs through biosynthetic medicinal chemistry

Matthew A. Gregory, Andrew L. Kaja, Steven G. Kendrew,

Chemical Science

2012

20

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