Long-Acting FGF21 Has Enhanced Efficacy in Diet-Induced Obese Mice and in Obese Rhesus Monkeys

Murielle M. Véniant, Renée Komorowski, Ping Chen, +7

Endocrinology

NutritionMetabolic DisorderMurine Recombinant Fgf21ObesityMetabolic Syndrome +15

Fully Human Monoclonal Antibodies Antagonizing the Glucagon Receptor Improve Glucose Homeostasis in Mice and Monkeys

Hai Yan, Wei Gu, Jie Yang, +16

Journal of Pharmacology and Experimental Therapeutics

Expression of helix-loop-helix regulatory genes during differentiation of mouse osteoblastic cells

Samuel S. Murray, Carlotta A. Glackin, Katherine A. Winters, +3

Journal of Bone and Mineral Research

Long-Term Inhibition of the Glucagon Receptor with a Monoclonal Antibody in Mice Causes Sustained Improvement in Glycemic Control, with Reversible α-Cell Hyperplasia and Hyperglucagonemia

Wei Gu, Hai Yan, Katherine A. Winters, +12

Journal of Pharmacology and Experimental Therapeutics

Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity

Les P. Miranda, Katherine A. Winters, Colin V. Gegg, +12

Journal of Medicinal Chemistry

EngineeringPeptide EngineeringGlycobiologyMolecular BiologyChemical Biology +16

Improvements to the Operational Tropical Cyclone Wind Speed Probability Model

Mark DeMaria, John A. Knaff, Michael J. Brennan, +9

Weather and Forecasting

Storm SurgeEngineeringCoastal ModelingClimate ModelingWeather Forecasting +23

Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor

Wei Gu, Katherine A. Winters, Alykhan Motani, +12

American Journal of Physiology-Endocrinology and Metabolism

Metabolic SyndromeGlucose ToleranceDiabetes ManagementMedicineInsulin Management +13

Pharmacological Targeting of Glucagon and Glucagon-Like Peptide 1 Receptors Has Different Effects on Energy State and Glucose Homeostasis in Diet-Induced Obese Mice

Wei Gu, David J. Lloyd, Narumol Chinookswong, +8

Journal of Pharmacology and Experimental Therapeutics

Bicistronic and Two-Gene Retroviral Vectors for UsingMDR1 as a Selectable Marker and a Therapeutic Gene

Marianne Z. Metz, Linda Matsumoto, Katherine A. Winters, +2

Virology

Selectable MarkerTwo-gene Retroviral VectorsHuman RetrovirusImmunologyVirology +6

Objective Guidance for Use in Setting Tropical Cyclone Conditions of Readiness

Charles R. Sampson, Andrea Schumacher, John A. Knaff, +6

Weather and Forecasting

NursingMeteorologyWind Probability ThresholdsWeather ModificationEngineering +10