Isotopic Effect Study of Propofol Deuteration on the Metabolism, Activity, and Toxicity of the Anesthetic

Julie Helfenbein, Claire Lartigue, E. Miot Noirault, +4

Journal of Medicinal Chemistry

BiochemistryPropofol DeuterationIsotopic Effect StudyIsotopic SubstitutionMedicine +13

Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET

Frédéric Dollé, Patrick Emond, Sylvie Mavel, +13

Bioorganic & Medicinal Chemistry

Positron Emission TomographyEngineeringSelective RadioligandDopamine TransporterRadionuclide Therapy +10

Pharmacological Characterization of (E)-N-(4-Fluorobut-2-enyl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (LBT-999) as a Highly Promising Fluorinated Ligand for the Dopamine Transporter

Sylvie Chalon, Håkan Hall, Wadad Saba, +12

Journal of Pharmacology and Experimental Therapeutics

Radiosynthesis of [¹⁸F]LBT‐999, a selective radioligand for the visualization of the dopamine transporter with PET

Frédéric Dollé, Françoise Hinnen, Patrick Emond, +14

Journal of Labelled Compounds and Radiopharmaceuticals

PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter

Julie Helfenbein, Johan Sandell, Christer Halldin, +11

Nuclear Medicine and Biology

Molecular PharmacologyAddictionMedicinePotent Cocaine DerivativesNeurotransmitter +8

One‐step radiosynthesis of [¹⁸F]LBT‐999: a selective radioligand for the visualization of the dopamine transporter with PET

Frédéric Dollé, Julie Helfenbein, Françoise Hinnen, +14

Journal of Labelled Compounds and Radiopharmaceuticals

NeurotransmitterOrganic ChemistryChemistryPharmaceutical ChemistryPositron Emission Tomography +23

[¹¹C]LBT‐999: A suitable radioligand for investigation of extra‐striatal dopamine transporter with PET

Wadad Saba, Héric Valette, Marie‐Anne Schöllhorn‐Peyronneau, +11

Synapse

Synthesis of Tropane and Nortropane Analogues with Phenyl Substitutions as Serotonin Transporter Ligands

Patrick Emond, Julie Helfenbein, Sylvie Chalon, +5

Bioorganic & Medicinal Chemistry

Combinatorial ChemistryPhenyl SubstitutionsEngineeringMedicineDrug Discovery +7

A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: Pharmacological evaluation and pet experiments

Julie Helfenbein, Christian Loc’h, Michel Bottlaender, +10

Life Sciences

Positron Emission TomographySubstance AbuseAddictionMedicineClub Drug +12