Nobuyuki Ae

Tricyclic Quinoxalinediones: 5,6-Dihydro-1H-pyrrolo[1,2,3-de]quinoxaline-2,3-diones and 6,7-Dihydro-1H,5H-pyrido[1,2,3-de]quinoxaline-2,3-diones as Potent Antagonists for the Glycine Binding Site of the NMDA Receptor

Ryu Nagata, Norihiko Tanno, Toru Kodo et al. · Journal of Medicinal Chemistry · 1994 · 71 citations

Combinatorial Chemistry, Pharmacotherapy, Heterocycle Chemistry +19

Synthesis of Tricyclic Indole-2-caboxylic Acids as Potent NMDA-Glycine Antagonists

Seiji Katayama, Nobuyuki Ae, Ryu Nagata · The Journal of Organic Chemistry · 2001 · 49 citations

Nmda-glycine Binding Site, Medicine, Pharmacological Agent +10

Enzymatic resolution of 2-substituted tetrahydroquinolines. Convenient approaches to tricyclic quinoxalinediones as potent NMDA-glycine antagonists

Seiji Katayama, Nobuyuki Ae, Ryu Nagata · Tetrahedron Asymmetry · 1998 · 43 citations

Molecular Pharmacology, Bioorganic Chemistry, Biochemistry +10

Structure-activity relationships of tricyclic quinoxalinediones as potent antagonists for the glycine binding site of the NMDA receptor 1

Ryu Nagata, Nobuyuki Ae, Norihiko Tanno · Bioorganic & Medicinal Chemistry Letters · 1995 · 26 citations

Biochemistry, Functional Selectivity, Medicine +8

Tricyclic Indole-2-carboxylic Acids:  Highly in Vivo Active and Selective Antagonists for the Glycine Binding Site of the NMDA Receptor

Seiji Katayama, Nobuyuki Ae, Toru Kodo et al. · Journal of Medicinal Chemistry · 2003 · 25 citations · Full text

Nmda-glycine Binding Site, Pharmacotherapy, Pharmaceutical Chemistry +18