Malha Sahmi

A dimerization-dependent mechanism drives RAF catalytic activation

Thanashan Rajakulendran, Malha Sahmi, Martin Lefrançois et al. · Nature · 2009 · 488 citations

Catalysis, Molecular Catalysis, Biochemistry +1

MEK drives BRAF activation through allosteric control of KSR proteins

Hugo Lavoie, Malha Sahmi, Pierre Maisonneuve et al. · Nature · 2018 · 151 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +10

RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition

Ting Jin, Hugo Lavoie, Malha Sahmi et al. · Nature Communications · 2017 · 103 citations · Full text

A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila

Dariel Ashton‐Beaucage, Christian M. Udell, Patrick Gendron et al. · PLoS Biology · 2014 · 65 citations · Full text

Genetics, Genomic Mechanism, Molecular Genetics +19

Control of oestradiol secretion and of cytochrome P450 aromatase messenger ribonucleic acid accumulation by FSH involves different intracellular pathways in oestrogenic bovine granulosa cells <i>in vitro</i>

J M Silva, Mélanie Hamel, Malha Sahmi et al. · Reproduction · 2006 · 59 citations