Lynette Knowles

Targeted Induction of Endoplasmic Reticulum Stress Induces Cartilage Pathology

M. Helen Rajpar, Ben McDermott, Louise H. W. Kung et al. · PLoS Genetics · 2009 · 132 citations · Full text

Engineering, Cell Death, Er Stress +20

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

Katarzyna A. Piróg, Roger S. Meadows, Lynette Knowles et al. · Human Molecular Genetics · 2007 · 94 citations · Full text

Mitophagy, Apoptosis, Psach Patients +21

Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation

Matthew Leighton, Seema Nundlall, Tobias Starborg et al. · Human Molecular Genetics · 2007 · 79 citations · Full text

Activation of extracellular signal-regulated protein kinase 5 downregulates FasL upon osmotic stress

X Wang, Katherine G. Finegan, Andrew Robinson et al. · Cell Death and Differentiation · 2006 · 58 citations · Full text

Cell Physiology, Signal Transduction, Signaling Pathway +13