Sofie Seghers

mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells

Sanne Bevers, Sander A. A. Kooijmans, Elien Van de Velde et al. · Molecular Therapy · 2022 · 133 citations · Full text

Medicine, Cancer Biology, Immunology +17

Efficient Continuous-Flow Bromination of Methylsulfones and Methanesulfonates and Continuous Synthesis of Hypobromite

Frederik E. A. Van Waes, Sofie Seghers, Wim Dermaut et al. · Journal of Flow Chemistry · 2014 · 20 citations

Natural Sciences, Chemical Engineering, Chemistry +10

Development and validation of the Normalized Organoid Growth Rate (NOGR) metric in brightfield imaging-based assays

Christophe Deben, Edgar Cardenas De La Hoz, Felicia Rodrigues Fortes et al. · Communications Biology · 2024 · 19 citations · Full text

Medicine, Cancer Biology, Oncology +16

Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition

Christophe Deben, Laurie Freire Boullosa, Felicia Rodrigues Fortes et al. · Journal of Experimental & Clinical Cancer Research · 2024 · 17 citations · Full text

Medicine, Oncology, Pharmacology +17

Design of a Mesoscale Continuous‐Flow Route toward Lithiated Methoxyallene

Sofie Seghers, Thomas S. A. Heugebaert, Matthias Moens et al. · ChemSusChem · 2018 · 12 citations

Pharmacy, Chemical Engineering, Medicinal Chemistry +13