Altered glycosylation of IgG4 promotes lectin complement pathway activation in anti-PLA2R1–associated membranous nephropathy

George Haddad, Johan M. Lorenzen, Hong Ma, +15

Journal of Clinical Investigation

MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked

József Dobó, Dávid Szakács, Gábor Oroszlán, +7

Scientific Reports

Crystal structure of the S100A4–nonmuscle myosin IIA tail fragment complex reveals an asymmetric target binding mechanism

Bence Kiss, Annette Duelli, László Radnai, +3

Proceedings of the National Academy of Sciences

Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding

Péter Ecsédi, Bence Kiss, Gergő Gógl, +11

Structure

Protein FunctionSignal TransductionBiochemistryProtein FoldingNatural Sciences +9

Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein

Gergő Gógl, Anita Alexa, Bence Kiss, +5

Journal of Biological Chemistry

Protein FunctionS100b ProteinMolecular BiologyStructural BasisMedicine +4

Affinity, Avidity, and Kinetics of Target Sequence Binding to LC8 Dynein Light Chain Isoforms

László Radnai, Péter Rapali, Zsuzsa Hódi, +9

Journal of Biological Chemistry

BiochemistryProtein FoldingNatural SciencesMacromolecular MachineMolecular Biology +3

Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway

Gábor Erdős, Tamás Szaniszló, Mátyás Pajkos, +5

PLoS Computational Biology

Hub ProteinMolecular BiologyCytoskeletonLinear MotifsSignaling Pathway +24

Structure Determination of the Transactivation Domain of p53 in Complex with S100A4 Using Annexin A2 as a Crystallization Chaperone

Péter Ecsédi, Gergő Gógl, Henrietta Hóf, +3

Structure

Transactivation DomainProtein AssemblyNatural SciencesCrystallization ChaperoneProtein X-ray Crystallography +6

Ezrin interacts with S100A4 via both its N- and C-terminal domains

Beáta Biri‐Kovács, Bence Kiss, Henrietta Vadászi, +6

PLoS ONE

Nmr SpectroscopyCell AdhesionMolecular BiologyCytoskeletonCellular Physiology +14

Multiple S100 protein isoforms and C-terminal phosphorylation contribute to the paralog-selective regulation of nonmuscle myosin 2 filaments

Péter Ecsédi, Neil Billington, Gyula Pálfy, +6

Journal of Biological Chemistry

Molecular PhysiologySignal TransductionC-terminal Phosphorylation ContributeMedicineParalog-selective Regulation +9