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Science

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A Pliable Mediator Acts as a Functional Rather Than an Architectural Bridge between Promoters and Enhancers

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SARS-CoV-2 drives JAK1/2-dependent local complement hyperactivation

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Science Immunology

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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells

Daniel Chauss, Tilo Freiwald, Reuben McGregor, +26

Nature Immunology

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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells

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Nature Immunology

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Aberrant type 1 immunity drives susceptibility to mucosal fungal infections

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Science

Autophagy and mitophagy participate in ocular lens organelle degradation

M. Joseph Costello, Lisa Brennan, Subhasree Basu, +6

Experimental Eye Research

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Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa

Giovanni A. M. Povoleri, Estefanía Nova‐Lamperti, Cristiano Scottà, +22

Nature Immunology

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Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

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Immunity

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C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection

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Cell

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