Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study

David Adams, Michael Polydefkis, Alejandra González‐Duarte, +437

The Lancet Neurology

Alzheimer's DiseaseOpen-label Extension StudyMedicineHereditary Transthyretin-mediated AmyloidosisNeurology +3

Dopamine receptor type 2 (<scp>DRD2</scp>) and somatostatin receptor type 2 (<scp>SSTR2</scp>) agonists are effective in inhibiting proliferation of progenitor/stem‐like cells isolated from nonfunctioning pituitary tumors

Erika Peverelli, Elena Giardino, Donatella Treppiedi, +19

International Journal of Cancer

Filamin A (FLNA) Plays an Essential Role in Somatostatin Receptor 2 (SST2) Signaling and Stabilization After Agonist Stimulation in Human and Rat Somatotroph Tumor Cells

Erika Peverelli, Elena Giardino, Donatella Treppiedi, +7

Endocrinology

Cancer BiologyTumor BiologyEndocrine OncologySignaling PathwayCancer Cell Biology +18

Cyclic adenosine 3′-5′-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac)

Eleonora Vitali, Erika Peverelli, Elena Giardino, +6

Molecular and Cellular Endocrinology

Pituitary CellsSignal TransductionMolecular PhysiologyCyclic AdenosineExchange Proteins +12

Screening for GNAS genetic and epigenetic alterations in progressive osseous heteroplasia: First Italian series

Francesca Marta Elli, Anna Maria Barbieri, Paolo Bordogna, +7

Bone

Progressive Osseous HeteroplasiaDevelopmental BiologySomatic VariantMendelian DisorderEpigenetic Alterations +9

Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation

Erika Peverelli, Elena Giardino, Donatella Treppiedi, +7

Cancer Letters

Developmental BiologySignal TransductionPituitary GlandFunctional SelectivityCell Trafficking +9

cAMP/PKA-induced filamin A (FLNA) phosphorylation inhibits SST2 signal transduction in GH-secreting pituitary tumor cells

Erika Peverelli, Elena Giardino, Federica Mangili, +9

Cancer Letters

Signal TransductionPituitary GlandEndocrine MechanismSignaling PathwayCamp/pka-induced Filamin A +9

A novel pathway activated by somatostatin receptor type 2 (SST2): Inhibition of pituitary tumor cell migration and invasion through cytoskeleton protein recruitment

Erika Peverelli, Elena Giardino, Donatella Treppiedi, +7

International Journal of Cancer

Human GrowthNovel PathwayCollagen IvGh SecretionTumor Biology +22

Specific roles of Gi protein family members revealed by dissecting SST5 coupling in human pituitary cells

Erika Peverelli, Marta Busnelli, Eleonora Vitali, +7

Journal of Cell Science

Single-Molecule Microscopy Reveals Dynamic FLNA Interactions Governing SSTR2 Clustering and Internalization

Donatella Treppiedi, Marie‐Lise Jobin, Erika Peverelli, +7

Endocrinology

Cell AdhesionMolecular BiologyCytoskeletonCellular PhysiologySstr2 Internalization +21