Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

Xianghai Liao, Judith C. Sluimer, Ying Wang, +6

Cell Metabolism

InflammationCell AutophagyMitophagyMacrophage AutophagyAutophagy +7

Macrophage Metabolism of Apoptotic Cell-Derived Arginine Promotes Continual Efferocytosis and Resolution of Injury

Arif Yurdagul, Manikandan Subramanian, Xiaobo Wang, +13

Cell Metabolism

InflammationSignal TransductionCell SignalingApoptosisImmunology +8

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

Kristin Westphalen, Galina A. Gusarova, Mohammad Naimul Islam, +4

Nature

InflammationLung InflammationInnate Immune SystemImmunologyImmunologic Mechanism +7

Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution

Jonathan D. Proto, Amanda C. Doran, Galina A. Gusarova, +10

Immunity

InflammationAutoimmune DiseaseT-regulatory CellImmune RegulationImmunology +5

Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages

Ying Wang, Manikandan Subramanian, Arif Yurdagul, +7

Cell

MitophagyMitochondrial FunctionMitochondrial DynamicMedicineApoptosis +11

Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

Edward B. Thorp, Tomáš Vaisar, Manikandan Subramanian, +3

Journal of Biological Chemistry

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

Bishuang Cai, Edward B. Thorp, Amanda C. Doran, +6

Proceedings of the National Academy of Sciences

ImmunologyCell DeathOxidative StressInflammationSignaling Pathway +18

Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles

Nazila Kamaly, Gabrielle Fredman, Manikandan Subramanian, +7

Proceedings of the National Academy of Sciences

Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis

Nazila Kamaly, Gabrielle Fredman, Jhalique Jane R. Fojas, +16

ACS Nano

NanoparticlesNanotherapeuticsEngineeringImmunologyScreen Nanoparticles +20

Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs

Manikandan Subramanian, Edward B. Thorp, Göran K. Hansson, +1

Journal of Clinical Investigation